Almost all links are to the COS Funding Opportunities website. If you are off-campus you will need to register as a Missouri State member.
Leveraging Existing Data or Longitudinal Studies to Evaluate Safety and Effectiveness of Pharmacological Management of Chronic Pain in Older Adults (R03)
This FOA solicits projects that aim to leverage existing data or longitudinal studies in order to evaluate the safety and/or effectiveness of pharmacological management for chronic pain in older adults. Applicants are invited to submit innovative proposals using administrative databases, health care records, clinical trial datasets, patient registries, cohort studies, or other resources to further our understanding of treatment outcomes from pharmacologic or combination pharmacologic/non-pharmacologic interventions, particularly involving non-steroidal anti-inflammatory drugs (NSAIDs) or opioids, in older individuals with chronic pain. Proposed studies may include, but are not limited to 1) identification of patient-, medication-, provider-, or system-level predictors of treatment outcomes in older individuals; 2) comparative safety and/or effectiveness studies of different treatment approaches for chronic pain in older adults; 3) development of methodologies linking datasets to address pain-related questions; or 4) evaluation of the utility of pain-related measures or indices in guiding treatment initiation, titration, or discontinuation in specific populations of older adults (e.g., individuals with dementia.)
Letter of Intent (not required) Deadline: October 3, 2011
Application Deadline: November 30, 2011
Funding Agency: National Institutes of Health
Oceans, Great Lakes and Human Health (R01)
This FOA solicits grant applications that address research approaches to problems that are relevant to oceans and human health. The purpose of Oceans, Great Lakes and Human Health (OGLHH) is to provide linkages between members of the ocean sciences and biomedical communities in order to support interdisciplinary research in areas where improved understanding of marine processes and systems has potential to reduce public health risks. This FOA will solicit grant applications that address marine or Great Lakes harmful algal bloom (HAB) research, marine or Great Lakes pollution, (e.g., chemical toxicants assessment of long-term chronic exposures versus acute exposures; aspects of global climate change that influence ocean or Great Lakes related human health outcomes; and development of statistical and bioinformatic tools to link developed oceanographic or Great Lakes models with less well developed human health exposure and disease models.) OHH awards are expected to create an environment conducive to interdisciplinary and reciprocally beneficial collaborations among biomedical scientists (e.g., epidemiologists, pharmacologists, toxicologists, microbiologists, cell and molecular biologists) and ocean scientists (e.g., biological and physical oceanographers, geochemists, and ecologists) with the common goal of improving our knowledge of the impacts of the ocean and Great Lakes on human health.
Letter of Intent (not required) Deadline: October 22, 2011
Application Deadline: November 22, 2011
Funding Agency: National Institutes of Health
Environmental Influences on Stem Cells in Development, Health, and Disease (R01)
The goal of this initiative is to support novel research directions leading to understanding the potential of environmental exposures to alter function, proliferation, survival, and differentiation of stem cells, including embryonic and adult pluripotent and multipotent cells.
Letter of Intent (strongly suggested) Deadline: October 28, 2011
Application Deadline: November 28, 2011
Funding Agency: National Institutes of Health
Mechanistic Pathways Linking Psychosocial Stress and Behavior (R01)
This Funding Opportunity Announcement (FOA) issued by the NIH Basic Behavioral and Social Sciences Opportunity Network (OppNet) solicits Research Project grant (R01) applications from institutions and organizations that propose to investigate basic psychological, social, and environmental mechanisms and processes linking psychosocial stressors and behavior. This FOA will facilitate investigation of multiple and potentially bidirectional pathways underlying the behavioral, environmental, and psychosocial link(s) between psychosocial stressors and behaviors that may ultimately impact biological function, health, and disease. Applicants are encouraged to use innovative and integrative designs to elucidate how psychological, social, and psychosocial environmental factors impact the processes by which stressors become coupled with and influenced by behaviors. Applications examining moderating factors such as individual demographic (age, gender/sex, ethnicity) and psychological (vulnerabilities, resilience) differences, risk factors, timing of exposure to stressors, and environments are desirable. This research will provide a deeper understanding of the psychological, environmental, and social processes that ultimately connect psychosocial stress and behaviors and consequently physiological processes, health, and disease.
Letter of Intent (strongly suggested) Deadline: November 19, 2011
Application Deadline: December 19, 2011
Funding Agency: National Institutes of Health
Application of Genomic Advances to Wound Repair (R01)
The National Institute of Nursing Research seeks to stimulate research that will increase the understanding of the genomic mechanisms associated with development and repair of chronic wounds (wounds that have not proceeded through a reparative process in three months), and to develop and test genomic-based interventions aimed at preventing chronic wounds and/or expediting the healing process. It is anticipated that the findings from this research will expand the body of knowledge needed to identify individuals at the highest risk for developing chronic wounds and to inform the search for customized therapeutics and interventions tailored to an individual’s genomic profile.
Letter of Intent (requested) Deadline: December 23, 2011
Application Deadline: January 23, 2012
Funding Agency: National Institutes of Health
Initiative for Maximizing Student Development (IMSD) (R25)
The goal of the IMSD Program is to increase the number of students from groups underrepresented in the biomedical and behavioral sciences that complete the Ph.D. degree in these fields at institutions with research intensive environments. The program provides institutional grants to establish research training programs at institutions with research intensive environments that will increase the preparation and skills of underrepresented students in the biomedical and behavioral sciences as they academically advance in the pursuit of the Ph.D. degree in these fields.
Application Deadline: January 25, 2012
Funding Agency: National Institutes of Health
Healthy Homes Technical Studies Program
The overall goal of the Healthy Homes Technical Studies program is to gain knowledge to improve the efficacy and cost-effectiveness of methods for the evaluation and control of housing related health and safety hazards. This also supports HUD’s Strategic Goal to utilize housing as a platform for improving the quality of life and health outcomes for those living in HUD-assisted and HUD-regulated housing, and the associated policy priority to build inclusive and sustainable communities by improving the health of community residents while reducing the impact of communities on the environment. The overall goals and objectives of the Healthy Homes (HH) Program are to (1) mobilize public and private resources, involving cooperation among all levels of government, the private sector, grassroots community-based organizations, including faith-based organizations, and other nonprofit organizations, to develop and implement the most promising, cost-effective methods for identifying and controlling housing-related hazards; and (2) build local capacity to operate sustainable programs that will continue to prevent, minimize, and control housing-related hazards in low- and very low-income residences when HUD funding is exhausted.
Application Deadline: January 31, 2012
Funding Agency: U.S. Department of Housing and Urban Development (HUD)
Practical Interventions to Improve Medication Adherence in Primary Care (R01)
This FOA is being issued by the NIH Adherence Network through the Office of Behavioral and Social Sciences Research (OBSSR), with participation from the National Cancer Institute (NCI), the National Eye Institute (NEI), the National Heart, Lung, and Blood Institute (NHLBI), the National Institute on Aging (NIA), the National Institute on Deafness and Other Communication Disorders (NIDCD), the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), the National Institute of Mental Health (NIMH), the National Institute of Nursing Research (NINR), and the National Center for Complementary and Alternative Medicine (NCCAM).
This FOA seeks Research Project Grant (R01) applications that propose practical interventions to improve adherence to medication. This FOA will support research to test interventions with the potential to significantly improve medication adherence in patients with chronic health conditions in settings where primary health care is delivered (including, dental and eye care settings). Applications may target medication adherence in the context of treatment for a single illness or chronic condition (e.g., hypertension) or multiple comorbid conditions (e.g., hypertension and HIV/AIDS). Studies should use the most rigorous design and methodology possible given the populations and settings in which the study is taking place. Primary outcomes of the research should include: a patient self-report of medication adherence, and at least one other non-self-report measure of medication adherence (e.g., pharmacy refill records, electronic monitoring, etc.). In addition, applications should include a health outcome or biomarker (e.g., blood pressure, viral load in HIV patients, cholesterol levels, HbA1c) that is expected to be affected by changes in the targeted adherence behavior. Researchers should address the capacity of the tested approach for wide dissemination, the sustainability of the approach once the research is concluded, and are encouraged to include measurement and costs of the intervention characteristics and contextual factors that affect implementation and adoption.
Application Deadline: February 5, 2012
Funding Agency: National Institutes of Health
Social Neuroscience and Neuroeconomics of Aging (R01)
The NIA issues this FOA with special review to stimulate interdisciplinary aging-relevant research in the social, affective and economic neurosciences. The NIA invites applications examining social, emotional and economic behaviors of relevance to aging, using approaches that examine mechanisms and processes at both (a) the social, behavioral or psychological (emotional, cognitive, motivational) level, and (b) the neurobiological or genetic level. Proposals are encouraged that have an overriding emphasis on economic, social or emotional processes and associated genetic or neurobiological processes. Applications should demonstrate either relevance for aging or for age differences or age-related changes in these processes. Aging-relevant applications can address issues of importance to the well-being and health of either mid-life or older adults, and can include data spanning the entire life course.
The NIA also encourages research projects that propose advances in measurement of economic and social phenotypes. Research is needed to identify core psychological and behavioral constructs and intermediary neurobiological phenotypes responsible for individual differences in economic and socioemotional behaviors, to enhance the potential for their application to life course genetic studies. There is an increasing need for measures that are harmonizable (to enable data pooling and cross-study comparisons) and flexible (capable of application across laboratory and field contexts).
The companion FOA is PAR-11-336, R21 Exploratory/Developmental Grant.
Application Deadline: February 5, 2012
Funding Agency: National Institutes of Health – National Institute on Aging
AHRQ Health Services Research Projects (R01)
This FOA solicits large research (R01) projects, and expresses the Agency for Healthcare Research and Quality(AHRQ) portfolio priority areas of interest for ongoing extramural health services research, demonstration, dissemination, and evaluation grants.
Application Deadline: February 5, 2012
Funding Agency: U.S. Department of Health and Human Services
Women’s Mental Health and Sex/Gender Differences Research (R01)
This FOA encourages grant applications from institutions and organizations that propose to study women’s mental health and sex/gender differences in mental health.
Application Deadline: February 5, 2012
Funding Agency: National Institutes of Health
Research on Ethical Issues in Biomedical, Social and Behavioral Research (R03)
The purpose of this FOA is to support investigator-initiated Small Research Grant Award (R03) applications that propose to study high priority bioethical challenges and issues associated with the types of biomedical, social and behavioral research supported by the participating NIH Institutes/Centers. The Office of Behavioral and Social Sciences Research (OBSSR) joins this FOA as part of its efforts to promote research on the behavioral and social aspects of health and illness. However, only participating ICs will provide direct grant support under this FOA.
Applications should address bioethical challenges and ethical issues relevant to the research mission area(s) of the participating NIH Institutes and Centers (ICs). The participating ICs have identified specific bioethics topics below as the highest priority for consideration. These are organized into seven categories:
1. Ethical considerations of new and emerging technologies;
2. Research study design issues
3. Issues associated with therapeutic misconception and the interface between treatment and research
4. Research involving vulnerable populations and urgent situations
5. Research with existing specimens, data, and health information
6. Dissemination and translation of research findings
7. Oversight of research
Applications that address other bioethical issues directly related to these mission areas will also be considered.
Application Deadline: February 16, 2012
Funding Agency: National Institutes of Health
Women and Sex/Gender Differences in Drug and Alcohol Abuse/Dependence (R03)
(This is anticipated funding)
The purpose of this Funding Opportunity Announcement (FOA) issued by the National Institute on Drug Abuse (NIDA) and National Institute on Alcohol Abuse and Alcoholism (NIAAA) is to advance research on male-females differences in drug and alcohol abuse and addiction and on factors specific to women. Both human and animal model studies are sought.
Application Deadline: February 16, 2012
Funding Agency: National Institutes of Health
NIH Competitive Revision Applications for Research Relevant to the Family Smoking Prevention and Tobacco Control Act (R01)
This FOA invites revision research project grant (R01) applications from investigators with active R01 research project awards issued by one of the participating Institute/Centers (ICs) listed in the FOA to support an expansion of the scope of approved and funded R01 projects involving smoking and tobacco-related products and/or their constituents. Revision R01 applications for projects that have not originally focused on tobacco use are welcome provided that the proposed revision addresses the research priorities related to FDA regulatory authority that are identified in the FOA. The awards under this FOA will be administered by NIH using designated funds [from the Food and Drug Administration (FDA) Center for Tobacco Products (CTP)] for tobacco regulatory science mandated by the Family Smoking Prevention and Tobacco Control Act (FSPTCA), Public Law 111-31. The NIH and the FDA have formed an interagency partnership to foster research relevant to tobacco regulations. Within the framework of the Tobacco Control Act, the FDA and NIH share interest in supporting research to aid the development and evaluation of tobacco product regulations.
Projects resulting from this FOA are expected to serve the FDA by generating relevant findings and data needed to inform the regulation of the manufacture, distribution, and marketing of tobacco products to protect public health. Consistent with the FDA CTP mission, this FOA seeks competitive revision projects that address such aspects as
- the toxicity and use of new and emerging tobacco products;
- effective methods to substantially reduce the toxicity of tobacco products and smoke;
- effective methods to substantially reduce the overall addictiveness of cigarettes and other tobacco products; and
- consumer perceptions and behaviors related to tobacco products, claims, and communications regarding tobacco products.
The companion FOA is PAR-12-011 U01 Research Project – Cooperative Agreements.
Letter of Intent (requested) Deadline: January 30, 2012
Application Deadline: February 17, 2012
Funding Agency: National Institutes of Health
New Tools to Study Astrocyte Heterogeneity, Development and Function in Brain Regions Relevant to Mental Illness (R01)
This Funding Opportunity Announcement (FOA) encourages research grant applications that propose the development or adaptation of cutting edge technologies for astrocyte research, discovery-based research on astrocyte diversity, development and/or function in the brain, and the application of these to the study of basic brain processes or pathophysiology relevant to mental illnesses. The primary objective of this FOA is to address barriers to astrocyte research that are due to the scarcity of tools and datasets to target and identify astrocytes rigorously. Applications should aim to transform the field of astrocyte research by generating resources that will be widely used throughout the neuroscience community. Research supported by this initiative will:
1. Provide new tools for manipulating and identifying astrocytes based on their heterogeneity, developmental stage or functional state;
2. Identify novel phenomic signatures and combinatorial regulatory mechanisms of astrocyte development/function that account for astrocyte diversity;
3. Characterize mechanisms by which astrocytes regulate neural circuits serving cognition, emotion and social function or contribute to abnormal neural function relevant to psychopathology.
Letter of Intent (required) Deadline: February 9, 2012
Application Deadline: March 9, 2012
Funding Agency: National Institutes of Health
Environmental Health and Safety of Nanotechnology
The program provides support to develop and test the environmental effects of nanotechnologies.
Fundamental research is sought to understand, evaluate, and mitigate the impact of nanotechnology on the environment and biological systems. The program also supports research on the development and refinement of sensors and sensor network technologies that can be used to measure a wide variety of physical, chemical, and biological properties of interest in characterizing, monitoring, and understanding environmental impacts.
The program emphasizes engineering principles underlying the environmental health and safety impacts of nanotechnology. Innovative methods related to production processes, waste reduction, recycling, and industrial ecology of nanotechnology are of interest.
Current areas of support include
- understanding and mitigating the effects of nanotechnology and biotechnology on the environment;
- nanotechnology environmental health and safety impacts and applications;
- predictive methodology for the interaction of nanoparticles with the environment and with the human body, including predictive approaches for toxicity;
- fate and transport of natural, engineered, and incidental (by-product) nanoparticles; and
- risk assessment and management of the effect of nanomaterials in the environment.
Current areas of support for this program do not include biomedical and nanotoxicology topics involving clinical trials.
All proposed research should be driven by engineering principles, and presented in an environmental health and safety or environmental sensor context. Proposals should include involvement of at least one engineering student.
Proposals should address the novelty of the concept being proposed, compared to previous work in the field. Also, it is important to address why the novelty might be important in terms of engineering science, as well as to also project the potential impact on society and/or industry of success in the research. The information requested in this paragraph should be included, as a minimum, in the Project Summary of each proposal.
Application Deadline: February 17, 2012
Funding Agency: National Science Foundation
Affordable Care Act – Maternal, Infant, and Early Childhood Home Visiting Research Network
The purpose of this cooperative agreement is to support the creation of an interdisciplinary, multi-center research forum for scientific collaboration and infrastructure building related to home visiting research that is designed to improve life outcomes among mothers, infants, and young children. The work of this Network will complement the ongoing research and evaluation activities occurring both within the MIECHV program and in the research field broadly, and will have the following goals:
1. Develop a national research agenda designed to improve the implementation and effectiveness of maternal, infant, and early childhood home visiting programs through: (a) research on the components of effective interventions, and (b) research targeted to improving the delivery of home visiting services; this national research agenda will also be used to actively guide the Network’s implementation of research studies through both MCHB and external funding sources
2. Advance the methods of studying the implementation and effectiveness of home visiting programs
3. Develop approaches to data sharing that will expedite the translation of research results into knowledge, products, and procedures
4. Disseminate critical information and foster continued education activities on its research findings to inform researchers, professionals, policy makers, other stakeholders in the home visiting field, and the public
5. Support the professional development of emerging researchers to conduct research on home visiting through: fostering mentoring relationships between faculty members and emerging researchers; and encouraging active communication, networking, and collaboration among researchers
Types of relevant activities conducted by the Network may include but are not limited to the following:
1. Identifying effective approaches and/or testing the effectiveness of approaches to the implementation of evidence-based home visiting programs within communities
2. Identifying gaps in necessary program enhancements and/or testing the efficacy of enhancements to evidence-based home visiting programs, including but not limited to: culturally appropriate adaptations
3. Enhancements to address intimate-partner violence, substance abuse, and parental health and wellbeing; and/or enhancements related to improving the participant outcomes or benchmark domains specified in the Maternal, Infant, and Early Childhood Home Visiting legislation
4. Investigating mechanisms of change within program models or implementation systems in order to identify which program components work under which circumstances for which participants
5. Exploring the capacity of existing home visiting models and service systems to meet the unique developmental needs of pregnant and parenting adolescents
6. Determining effective program features that can improve participant recruitment/ retention, including father engagement
7. Developing approaches to screening children and families for variables highlighted as priority risk areas that can be used in conjunction with home visiting models
8. Identifying and evaluating community-based partnerships that enhance a program’s responsiveness to community needs
9. Evaluating and recommending coordinated approaches that support healthy development by fostering collaborations across diverse agencies that serve mothers and young children, including but not limited to early childhood education settings, health care providers, and local programs
10. Conducting cost-benefit analyses of home visiting programs
11. Fostering workforce development, specifically: effective techniques for reflective supervision; effective methods of training and continuing education for home visitors; recruitment and retention of effective home visitors; effective support for home visitor mental health; and other relevant topics
The activities described above may be supported in various ways, including but not limited to convening in-person, video, and teleconference meetings of network members and members of the public; and disseminating information through conference presentations, publications, webinars, and websites.
Application Deadline: March 5, 2012
Funding Agency: U.S. Department of Health and Human Services
Mechanism for Time-Sensitive Drug Abuse Research (R01)
This FOA is intended to support substance abuse prevention and treatment services research in rapidly evolving areas (e.g., changes in service systems, health care financing, policy, natural/man-made disasters) where opportunities for empirical study are, by their very nature, only available through expedited review and award of support. There are three distinguishing features of an eligible study: (1) the study’s scientific value and feasibility are clear, (2) rapid review and funding are required in order for the scientific question to be answered, and (3) the knowledge gained from the study is time-sensitive and seeking funding through the regular NIH cycle of review and award would result in a missed opportunity to conduct the research. It should be clear that the research question offers an uncommon and scientifically significant research opportunity that could only become available if the project is initiated with minimum delay.
Application Deadline: March 9, 2012
Funding Agency: National Institutes of Health
Reducing Health Disparities Among Minority and Underserved Children (R01)
This FOA, issued by the National Institute of Nursing Research (NINR), National Heart, Lung, and Blood Institute (NHLBI), National Institute on Alcohol, Alcoholism, and Alcohol Abuse (NIAAA), and National Institute on Deafness and Other Communication Disorders (NIDCD), National Institutes of Health (NIH), solicits Research Project Grant (R01) applications from institutions/organizations that propose to conduct research to reduce health disparities among minority and underserved children. Specifically, this initiative focuses on ethnic and racial minority children and underserved populations of children such as: children from low literacy, rural and low-income populations, geographically isolated children, hearing and visually impaired children, physically or mentally disabled children, children of migrant workers, children from immigrant and refugee families, and language minority children. Specific targeted areas of research include biobehavioral studies that incorporate multiple factors that influence child health disparities such as biological (e.g., genetics, cellular, organ systems), lifestyle factors, environmental (physical and family environments), social (e.g., peers), economic, institutional, and cultural and family influences; studies that target the specific health promotion needs of children with a known illness and/or disability; and studies that test and evaluate the comparative effectiveness of health promotion interventions conducted in traditional and nontraditional settings.
Application Deadline: June 5, 2012
Funding Agency: National Institutes of Health
AHRQ Small Research Grant Program (R03)
This FOA encourages Small Research Grant (R03) applications, and expresses AHRQ portfolio priority areas of interest for ongoing small research projects. The R03 grant mechanism supports different types of health services research projects including pilot and feasibility studies; secondary analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology.
Application Deadline: June 16, 2012
Funding Agency: Agency for Healthcare Research and Quality